We present HueRistic, an interactive system that optimizes color in live video through physical lighting control. Our system integrates a camera with programmable LED lights, analyzing the colors in the live feed and measuring the effect of each light source. HueRistic employs closed-loop optimization to find RGB lighting configurations that satisfy specific aesthetic objectives, such as enhancing color harmony or reproducing target colors in the scene. To support rapid exploration, HueRistic includes a design gallery that allows users to compare candidate lighting configurations before applying them to the scene. Our technical evaluation demonstrates that our system accurately simulates and produces high quality lighting solutions that satisfy aesthetic objectives. Our user study finds that HueRistic enables creators to discover lighting parameters that would be challenging to achieve through trial-and-error alone.